Women are more susceptible than men to the effects of wine—and of all other types of alcohol—even when weight is eliminated as a factor. Women have less aldehyde dehydrogenase-2 (ALDH2), the enzyme in the lining of the stomach that begins to break down and metabolize alcohol. Also, women’s bodies are 45% – 50% water, while a man’s is about 55% – 65%. As a result of both, when a man and a woman each drink the same amount of wine, more alcohol winds up in the bloodstream of the woman. According to one blood-alcohol concentration (BAC) study, 30 minutes after a 150-lb man and a 150-lb woman consume one drink with 0.6oz of alcohol, the man’s BAC is 0.018 and the woman’s is 0.027.