Women and men of the same size and body weight are equally affected by the alcohol in wine.
Women are more susceptible than men to the effects of wine—and of all other types of alcohol—even when weight is eliminated as a factor. Women have less aldehyde dehydrogenase-2 (ALDH2), the enzyme in the lining of the stomach that begins to break down and metabolize alcohol. Also, women’s bodies are 45% – 50% water, while a man’s is about 55% – 65%. As a result of both, when a man and a woman each drink the same amount of wine, more alcohol winds up in the bloodstream of the woman. According to one blood-alcohol concentration (BAC) study, 30 minutes after a 150-lb man and a 150-lb woman consume one drink with 0.6oz of alcohol, the man’s BAC is 0.018 and the woman’s is 0.027.